Bacillus subtilis is one of the best-characterised bacteria that is used as a model organism for Gram-positive bacteria. This rod-shaped bacterium produces endospores that allow for survival in extreme environmental conditions, including heat and extreme dryness. Ingestion of significant quantities of B. subtilis spores can help to restore normal gut microbiota following extensive antibiotic usage or illness by acting as an immunostimulatory agent. The non-pathogenic, spore-forming bacterium B. subtilis protects intestinal cells against oxidant-mediated tissue damage and loss of barrier function. Additionally, the improved expression and secretion of proteins by B. subtilis is an efficient tool for enzyme production, which accounts for around 60% of commercially available enzymes. 

Bacillus clausii is the probiotic of choice for digestive disorders, as it can form spores. It is, therefore, stable at room temperature and resistant to low pH levels, ensuring that it reaches the small intestine to colonise and release its beneficial effects. This spore-forming probiotic can inhibit the growth of pathogens in the gastrointestinal tract via three distinct mechanisms: colonisation of free ecological niches, which are no longer available for other microorganisms; competition for epithelial cell adhesion; and production of enzymes secreted into the intestinal environment. B. clausii is also a useful source for improving the intestinal imbalance of microbial flora and other intestinal malfunctions, thanks to its antimicrobial resistance features.

SpoGest-IB's probiotic strains can help produce metabolic compounds that suppress the growth of unwanted microorganisms (the ones that compete for receptors and binding sites with good microbes) on the intestinal mucosa. By doing so, you achieve a healthy, balanced state in your gut.

By repopulating and supporting beneficial gut bacteria and fixing an imbalance, SpoGest-IB strengthens the digestive system and regulates stool consistency. This helps give you regular, normal bowel movements on a daily basis.

The Bacillus probiotic strains of SpoGest-IB can enhance the integrity of the intestinal barrier and decrease translocation of bacteria across the intestinal mucosa. This allows proper maintenance of immune tolerance and better responsiveness from immune cells.

By nourishing healthy intestinal microflora, SpoGest-IB supports the building of a healthier, more resilient mind. Gut microbes may communicate with the gut–brain axis through the production of neuroactive and neuroendocrine molecules.

SpoGest-IB’s probiotics help improve nutrient status and tackle malabsorption issues by supporting the breakdown of food, proper small intestinal structure, and processes that lead to optimal nutrient use.